Linsdell, Paul : rechercher sur Z-Library

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1

Cystic fibrosis transmembrane conductance regulator (CFTR): Making an ion channel out of an active transporter structure

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 1.22 MB

english, 2018

2

Interactions between Impermeant Blocking Ions in the Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel Pore: Evidence for Anion-Induced Conformational Changes

Ning Ge, Paul Linsdell

Journal:

Journal of Membrane Biology

Année:

2006

Langue:

english

Fichier:

PDF, 1.25 MB

english, 2006

3

Direct and Indirect Effects of Mutations at the Outer Mouth of the Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel Pore

Jing-Jun Zhou, Mohammad Fatehi, Paul Linsdell

Journal:

Journal of Membrane Biology

Année:

2007

Langue:

english

Fichier:

PDF, 613 KB

english, 2007

4

Novel Residues Lining the CFTR Chloride Channel Pore Identified by Functional Modification of Introduced Cysteines

Mohammad Fatehi, Paul Linsdell

Journal:

Journal of Membrane Biology

Année:

2009

Langue:

english

Fichier:

PDF, 708 KB

english, 2009

5

Functional Differences in Pore Properties Between Wild-Type and Cysteine-Less Forms of the CFTR Chloride Channel

Ryan G. Holstead, Man-Song Li, Paul Linsdell

Journal:

Journal of Membrane Biology

Année:

2011

Langue:

english

Fichier:

PDF, 1.91 MB

english, 2011

6

Point mutations in the pore region directly or indirectly affect glibenclamide block of the CFTR chloride channel

Jyoti Gupta, Paul Linsdell

Journal:

Pflügers Archiv European Journal of Physiology

Année:

2002

Langue:

english

Fichier:

PDF, 145 KB

english, 2002

7

Exposure to sodium butyrate leads to functional downregulation of calcium-activated potassium channels in human airway epithelial cells

Jeremy Roy, Eileen M. Denovan-Wright, Paul Linsdell, Elizabeth A. Cowley

Journal:

Pflügers Archiv European Journal of Physiology

Année:

2006

Langue:

english

Fichier:

PDF, 358 KB

english, 2006

8

Involvement of tyrosine kinase in the hyposmotic stimulation ofIKsin guinea-pig ventricular myocytes

Sergey Missan, Paul Linsdell, Terence F. McDonald

Journal:

Pflügers Archiv European Journal of Physiology

Année:

2008

Langue:

english

Fichier:

PDF, 370 KB

english, 2008

9

Identification of positive charges situated at the outer mouth of the CFTR chloride channel pore

Jing-Jun Zhou, Mohammad Fatehi, Paul Linsdell

Journal:

Pflügers Archiv European Journal of Physiology

Année:

2008

Langue:

english

Fichier:

PDF, 496 KB

english, 2008

10

Regulation of wild-type and mutant KCNQ1/KCNE1 channels by tyrosine kinase

Sergey Missan, Jiansong Qi, Julie Crack, Terence F. McDonald, Paul Linsdell

Journal:

Pflügers Archiv European Journal of Physiology

Année:

2009

Langue:

english

Fichier:

PDF, 306 KB

english, 2009

11

Functional arrangement of the 12th transmembrane region in the CFTR chloride channel pore based on functional investigation of a cysteine-less CFTR variant

Feng Qian, Yassine El Hiani, Paul Linsdell

Journal:

Pflügers Archiv European Journal of Physiology

Année:

2011

Langue:

english

Fichier:

PDF, 593 KB

english, 2011

12

Non-pore lining amino acid side chains influence anion selectivity of the human CFTR Cl− channel expressed in mammalian cell lines

Paul Linsdell, Shu-Xian Zheng, John W. Hanrahan

Journal:

The Journal of Physiology

Année:

1998

Langue:

english

Fichier:

PDF, 692 KB

english, 1998

13

Relationship between anion binding and anion permeability revealed by mutagenesis within the cystic fibrosis transmembrane conductance regulator chloride channel pore

Journal:

The Journal of Physiology

Année:

2001

Langue:

english

Fichier:

PDF, 383 KB

english, 2001

14

Substrates of multidrug resistance-associated proteins block the cystic fibrosis transmembrane conductance regulator chloride channel

Paul Linsdell, John W Hanrahan

Journal:

British Journal of Pharmacology

Année:

1999

Langue:

english

Fichier:

PDF, 219 KB

english, 1999

15

Mechanism of lonidamine inhibition of the CFTR chloride channel

Xiandi Gong, Susan M Burbridge, Angie C Lewis, Patrick Y D Wong, Paul Linsdell

Journal:

British Journal of Pharmacology

Année:

2002

Langue:

english

Fichier:

PDF, 240 KB

english, 2002

16

Insensitivity of cardiac delayed-rectifier IKr to tyrosine phosphorylation inhibitors and stimulators

Sergey Missan, Pavel Zhabyeyev, Paul Linsdell, Terence F McDonald

Journal:

British Journal of Pharmacology

Année:

2006

Langue:

english

Fichier:

PDF, 208 KB

english, 2006

17

Mechanism of chloride permeation in the cystic fibrosis transmembrane conductance regulator chloride channel

Journal:

Experimental Physiology

Année:

2006

Langue:

english

Fichier:

PDF, 163 KB

english, 2006

18

Molecular determinants of Au(CN)2− binding and permeability within the cystic fibrosis transmembrane conductance regulator Cl− channel pore

Xiandi Gong, Susan M. Burbridge, Elizabeth A. Cowley, Paul Linsdell

Journal:

The Journal of Physiology

Année:

2002

Langue:

english

Fichier:

PDF, 357 KB

english, 2002

19

Multiple inhibitory effects of Au(CN)2− ions on cystic fibrosis transmembrane conductance regulator Cl− channel currents

Paul Linsdell, Xiandi Gong

Journal:

The Journal of Physiology

Année:

2002

Langue:

english

Fichier:

PDF, 430 KB

english, 2002

20

Characterization of basolateral K+ channels underlying anion secretion in the human airway cell line Calu-3

Elizabeth A. Cowley, Paul Linsdell

Journal:

The Journal of Physiology

Année:

2002

Langue:

english

Fichier:

PDF, 343 KB

english, 2002

21

Oxidant stress stimulates anion secretion from the human airway epithelial cell line calu-3: implications for cystic fibrosis lung disease

Elizabeth A. Cowley, Paul Linsdell

Journal:

The Journal of Physiology

Année:

2002

Langue:

english

Fichier:

PDF, 271 KB

english, 2002

22

Coupled Movement of Permeant and Blocking Ions in the CFTR Chloride Channel Pore

Xiandi Gong, Paul Linsdell

Journal:

The Journal of Physiology

Année:

2003

Langue:

english

Fichier:

PDF, 516 KB

english, 2003

23

Molecular Determinants and Role of An Anion Binding Site in the External Mouth of the CFTR Chloride Channel Pore

Xiandi Gong, Paul Linsdell

Journal:

The Journal of Physiology

Année:

2003

Langue:

english

Fichier:

PDF, 784 KB

english, 2003

24

Tyrosine kinase and phosphatase regulation of slow delayed-rectifier K+ current in guinea-pig ventricular myocytes

Sergey Missan, Paul Linsdell, Terence F. McDonald

Journal:

The Journal of Physiology

Année:

2006

Langue:

english

Fichier:

PDF, 551 KB

english, 2006

25

Selective block of swelling-activated Cl− channels over cAMP-dependent Cl− channels in ventricular myocytes

Lesya M Shuba, Sergey Missan, Pavel Zhabyeyev, Paul Linsdell, Terence F McDonald

Journal:

European Journal of Pharmacology

Année:

2004

Langue:

english

Fichier:

PDF, 259 KB

english, 2004

26

Molecular mechanism of arachidonic acid inhibition of the CFTR chloride channel

Jing-Jun Zhou, Paul Linsdell

Journal:

European Journal of Pharmacology

Année:

2007

Langue:

english

Fichier:

PDF, 170 KB

english, 2007

27

Direct block of the cystic fibrosis transmembrane conductance regulator Cl− channel by butyrate and phenylbutyrate

Journal:

European Journal of Pharmacology

Année:

2001

Langue:

english

Fichier:

PDF, 143 KB

english, 2001

28

Maximization of the rate of chloride conduction in the CFTR channel pore by ion–ion interactions

Xiandi Gong, Paul Linsdell

Journal:

Archives of Biochemistry and Biophysics

Année:

2004

Langue:

english

Fichier:

PDF, 206 KB

english, 2004

29

Role of kinases and G-proteins in the hyposmotic stimulation of cardiac IKs

Sergey Missan, Paul Linsdell, Terence F. McDonald

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Année:

2006

Langue:

english

Fichier:

PDF, 681 KB

english, 2006

30

Conformational change opening the CFTR chloride channel pore coupled to ATP-dependent gating

Wuyang Wang, Paul Linsdell

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Année:

2012

Langue:

english

Fichier:

PDF, 738 KB

english, 2012

31

Elevation of cytosolic calcium by cholinoceptor agonists in SH-SY5Y human neuroblastoma cells: estimation of the contribution of voltage-dependent currents

Ian D. Forsythe, David G. Lambert, Stefan R. Nahorski, Paul Linsdell

Journal:

British Journal of Pharmacology

Année:

1992

Langue:

english

Fichier:

PDF, 1.56 MB

english, 1992

32

Molecular Determinants of Anion Selectivity in the Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel Pore

Linsdell, Paul, Evagelidis, Alexandra, Hanrahan, John W.

Journal:

Biophysical Journal

Année:

2000

Langue:

english

Fichier:

PDF, 178 KB

english, 2000

33

Tuning of CFTR Chloride Channel Function by Location of Positive Charges within the Pore

El Hiani, Yassine, Linsdell, Paul

Journal:

Biophysical Journal

Année:

2012

Langue:

english

Fichier:

PDF, 1015 KB

english, 2012

34

Mechanism of direct bicarbonate transport by the CFTR anion channel

Lin Tang, Mohammad Fatehi, Paul Linsdell

Journal:

Journal of Cystic Fibrosis

Année:

2009

Langue:

english

Fichier:

PDF, 655 KB

english, 2009

35

Pseudohalide anions reveal a novel extracellular site for potentiators to increase CFTR function

Li, Man-Song, Cowley, Elizabeth A, Linsdell, Paul

Journal:

British Journal of Pharmacology

Année:

2012

Langue:

english

Fichier:

PDF, 2.84 MB

english, 2012

36

On the Origin of Asymmetric Interactions between Permeant Anions and the Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel Pore

Fatehi, Mohammad, St. Aubin, Chantal N., Linsdell, Paul

Journal:

Biophysical Journal

Année:

2007

Langue:

english

Fichier:

PDF, 257 KB

english, 2007

37

Relative contribution of different transmembrane segments to the CFTR chloride channel pore

Wang, Wuyang, Hiani, Yassine, Rubaiy, Hussein N., Linsdell, Paul

Journal:

Pflügers Archiv European Journal of Physiology

Année:

2014

Langue:

english

Fichier:

PDF, 989 KB

english, 2014

38

State-dependent blocker interactions with the CFTR chloride channel: implications for gating the pore

Journal:

Pflügers Archiv European Journal of Physiology

Année:

2014

Langue:

english

Fichier:

PDF, 916 KB

english, 2014

39

Role of the Juxtamembrane Region of Cytoplasmic Loop 3 in the Gating and Conductance of the Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel

El Hiani, Yassine, Linsdell, Paul

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 4.07 MB

english, 2012

40

Asymmetric Structure of the Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel Pore Suggested by Mutagenesis of the Twelfth Transmembrane Region †

Gupta, Jyoti, Evagelidis, Alexandra, Hanrahan, John W., Linsdell, Paul

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 105 KB

english, 2001

41

The cystic fibrosis transmembrane conductance regulator is an extracellular chloride sensor

Broadbent, Steven D., Ramjeesingh, Mohabir, Bear, Christine E., Argent, Barry E., Linsdell, Paul, Gray, Michael A.

Journal:

Pflügers Archiv European Journal of Physiology

Année:

2015

Langue:

english

Fichier:

PDF, 1.29 MB

english, 2015

42

Conformational changes opening and closing the CFTR chloride channel: Insights from cysteine scanning mutagenesis 1

El Hiani, Yassine, Linsdell, Paul

Journal:

Biochemistry and Cell Biology

Année:

2014

Fichier:

PDF, 227 KB

2014

43

Inhibition of cystic fibrosis transmembrane conductance regulator chloride channel currents by arachidonic acid

Journal:

Canadian Journal of Physiology and Pharmacology

Année:

2000

Fichier:

PDF, 267 KB

2000

44

Expression of the chloride channel CLC-K in human airway epithelial cells

Mummery, Jennifer L., Killey, Jennifer, Linsdell, Paul

Journal:

Canadian Journal of Physiology and Pharmacology

Année:

2005

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2005

45

Thiocyanate as a probe of the cystic fibrosis transmembrane conductance regulator chloride channel pore

Journal:

Canadian Journal of Physiology and Pharmacology

Année:

2001

Fichier:

PDF, 338 KB

2001

46

Extent of the selectivity filter conferred by the sixth transmembrane region in the CFTR chloride channel pore

Gupta, Jyoti, Linsdell, Paul

Journal:

Molecular Membrame Biology

Année:

2003

Langue:

english

Fichier:

PDF, 293 KB

english, 2003

47

Functional architecture of the CFTR chloride channel

Journal:

Molecular Membrame Biology

Année:

2014

Langue:

english

Fichier:

PDF, 1.26 MB

english, 2014

48

Evidence that extracellular anions interact with a site outside the CFTR chloride channel pore to modify channel properties

Zhou, Jing-Jun, Linsdell, Paul

Journal:

Canadian Journal of Physiology and Pharmacology

Année:

2009

Fichier:

PDF, 942 KB

2009

49

Location of a permeant anion binding site in the cystic fibrosis transmembrane conductance regulator chloride channel pore

Rubaiy, Hussein N., Linsdell, Paul

Journal:

The Journal of Physiological Sciences

Année:

2015

Langue:

english

Fichier:

PDF, 862 KB

english, 2015

50

Interactions between permeant and blocking anions inside the CFTR chloride channel pore

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Année:

2015

Langue:

english

Fichier:

PDF, 4.60 MB

english, 2015